Core Decompression in Osteonecrosis of the Femoral Head Where Do We Stand Today?
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Keywords
AVN; Hip joint; Stem cells; Cell therapy; PRP
Abstract
Early diagnosis and treatment with hip preservation procedures is the goal of osteonecrosis hip. Core decompression (CD) of the femoral head is a cost-effective procedure that reduces the intraosseous pressure, promotes neoangiogenesis, and enhances new bone formation. The need for the conversion of the total hip arthroplasty in the early-stage osteonecrosis hip is around 38% after an average follow-up of 26 months. The current techniques of CD involve multiple drilling (3 mm Steinmann pin) or drilling with large diame-ter reamers (5.0–7.2 mm) and numerous cellular and noncellular orthobiologic product instillations into the core tracks. The augmented CD with bone marrow aspirate concentrate (BMAC) or bone-marrow-derived mixed connective tissue progenitor’s cells instillation has consistently shown superior outcomes in early-stage osteonecrosis of the femoral head (ONFH; Ficat stage I and II and Association Research Circulation Osseous [ARCO] stage I and II). However, to date, no conclusive evidence supporting other orthobiologic products (platelet-rich plasma, bone morphogenetic protein, and tantalum) in ONFH is shown.