Tissue Wrapping Augmentation for Anterior Cruciate Ligament Reconstruction A Review of Clinical Literature

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George Jacob https://orcid.org/0000-0003-0744-1469
Kazunori Shimomura https://orcid.org/0000-0001-8931-146X
Yogesh K https://orcid.org/0000-0002-7078-0810
Norimasa Nakamura https://orcid.org/0000-0001-5631-4912


Biological ACL, Amnion, Periosteum, Tissue Wrapping


Anterior cruciate ligament reconstruction (ACLR) has become a popular surgery in orthopedic practice today, and the technique has evolved significantly over time. Surgical procedure, graft choice, and fixation systems have varied over the years. Nonetheless, several challenges like insufficient graft ligamentization, tunnel enlargement, and insufficient reestablishment of proprioception remain in ACLR. A vision of better graft healing and integration for improved outcomes after ACLR introduced the idea of the biological ACLR. Various techniques with growth factors, cellular therapies, or tissue augment have been researched with ACLR surgery for better integration and ligamentization. This review highlights the tissue wrapping
modalities currently being explored in biological ACLR.

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